Herpesvirus
NF-kappa B induction required in production of replication-competent HHV-8
Published in AIDS Weekly, September 27th, 2004
"The gammaherpesvirus human herpesvirus 8 (HHV-8) infects endothelial and B-lymphoid cells and is responsible for the development of Kaposi's sarcoma and primary effusion lymphoma (PEL).
"In the present study, we demonstrate that the activation of the NF-kappaB pathway during HHV-8 lytic replication is required for the generation of replication-competent virions capable of initiating a de novo infection of endothelial cells," researchers in Canada report.
"In the HHV-8-positive PEL cell line BCBL-1," wrote M. Sgarbanti and coworkers,...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
Source: AIDS Weekly (2004-09-27)
More Articles from AIDS Weekly
- HIV/AIDS Drug Resistance
Antiretroviral resistance mutations detected by high-density DNA probe arrays - HIV/AIDS Therapy
Baseline CD4 cell counts can guide initiation of HAART regardless of viral load - HIV/AIDS Therapy
Clinical benefits of tenofovir larger than predicted by plasma viral RNA levels - HIV/AIDS Therapy
Current guidelines to prevent opportunistic infections in HIV infection detailed - HIV/AIDS Therapy
Delavirdine boosts amprenavir trough levels more than 10-fold in children - AIDS Care
Partnership to bring anti-retroviral therapy to HIV/AIDS patients in India - More from this issue of AIDS Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
