Steroids
Oxandrolone blocks glucocorticoid signaling in androgen receptor-dependent way
Published in AIDS Weekly, September 27th, 2004
According to recent research published in the journal Steroids, "The anabolic steroid oxandrolone is increasingly used to preserve or restore muscle mass in those with HIV infection or serious burns. These effects are mediated, in part, by the androgen receptor (AR).
"Anti-glucocorticoid effects have also been reported for some anabolic steroids, and the goal of our studies was to determine whether oxandrolone had a similar mechanism of action."
"Studies with in vitro translated glucocorticoid receptor (GR), however, showed no inhibition...
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Source: AIDS Weekly (2004-09-27)
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