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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . October 11th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Epidemiology - HIV-1 subtypes unchanged among heterosexuals in England and Wales from 1997-2000

HIV/AIDS Therapy - HIV salvage therapy safe and effective in patients with >200 CD4+ cell counts

HIV/AIDS Therapy - Novel technique monitors safety/efficacy of HIV therapy

HIV/AIDS Therapy - Stereochemistry and regiochemistry of NNRTI profoundly affects anti-HIV activity

Human Immunodeficiency Virus - Targeting of HIV-1 RNA-DNA hybrid structures potential strategy for therapy

AIDS/HIV Therapy - Effort underway to improve the quality of HIV care in U.S.

AIDS/HIV Vaccine - Breakthrough infections occur during HIV-1 vaccine trials

AIDS/HIV Vaccine - Correlates of immune protection in HIV-1 infection reviewed

AIDS/HIV Vaccine - Development of AIDS vaccine from South African perspective presented

AIDS/HIV Vaccine - Filter for HIV-1 vaccine pipeline urgently needed

AIDS/HIV Vaccine - HIV and SIVCTL escape have implications for vaccine design

AIDS/HIV Vaccine - Polymeric microspheres deliver HIV Tat protein in vaccine applications

AIDS/HIV Vaccine - Poxvirus boost of DNA-primed monkeys augments peak lymphocyte responses

AIDS/HIV Vaccine - Program changes needed to introduce vaccines targeted at adolescents

Antimicrobials - Pesticide.net publishes article on antimicrobial technology

Antioxidants - Antioxidant intervention protective against oxidative DNA damage

Bacterial Resistance - MRSA isolated from the environment in a veterinary teaching hospital

Clinical Trials - Phase 2 clinical data indicate Remune induces HIV-specific immune response

Communicable Disease - Proposal would force treatment of communicable diseases

Complementary & Alternative Medicine - African patients with HIV seek out herbal remedies

Creutzfeldt-Jakob Disease - vCJD epidemic estimated at 150-500 deaths if 11-15 year incubation period

Drug Development - Bioscience company updates investors on development status of ZFP gene therapies

Drug Safety - Antiretroviral HIV therapy during pregnancy has special considerations

Esophageal Variceal Bleeding - Sanvar IR approved in Mexico for esophageal variceal bleeding, other indications

Feline Virus Infection - Viral infection outbreaks seen in cats in Wroclaw city area in Poland

Generic Drugs - FDA accepts NDA filing for megestrol acetate oral suspension NCD

Global Health - Combining TB treatment, HIV testing and treatment could save many African lives

HIV/AIDS - Reported Los Angeles County AIDS cases up 89% over past 2 years

HIV/AIDS Dementia - HIV dementia mechanism discovered

HIV/AIDS Detection - Confocal microscopy used to detect and quantitate HIV-1 particles

HIV/AIDS Drug Resistance - Only HR-1 sequencing necessary to characterize T-20 resistance in HIV infection

HIV/AIDS Epidemiology - AIDS epidemic poses serious threat to Europe

HIV/AIDS Epidemiology - Primary HIV-1 drug resistance is low in Brazil

HIV/AIDS Epidemiology - Traditional beliefs about cause of AIDS in South Africa lead to social stigmas

HIV/AIDS Funding - Group to support HIV/AIDS community for 3 more years with $1 million grant

HIV/AIDS Healthcare - HIV/AIDS healthcare infrastructure helps decrease risk of drug resistance

HIV/AIDS Healthcare - Psychological needs not being met for HIV-infected heterosexual men

HIV/AIDS Prevention - AIDS prevention programs can be transferred to developing countries

HIV/AIDS Prevention - American Indian center, Harm Reduction Project to track HIV/AIDS

HIV/AIDS Prevention - Asia must tackle HIV in injecting drug users

HIV/AIDS Prevention - California governor signs one needle bill, vetoes another

HIV/AIDS Research - APOBEC3F is suppressed by HIV-1 and HIV-2 Vif proteins

HIV/AIDS Research - Antiretroviral host factor APOBEC3G targets specific virus species

HIV/AIDS Research - Decreased T-cell proliferation is central in CD4 cell expansions induced by IL-2

HIV/AIDS Research - HIV Gag self-association is not significantly influence by the P2 domain

HIV/AIDS Research - HIV-1 Gag assembles to a capsid through the formation of the 60 S multimer

HIV/AIDS Research - HIV-1 Nef equips dendritic cells to reduce survival and function of CD8 cells

HIV/AIDS Research - Human cytidine deaminase APOBEC3G is a broad antiviral enzyme

HIV/AIDS Research - Impaired cytokine production may contribute to OI in patients with CD4 recovery

HIV/AIDS Research - Monocyte behavior in HIV-1 influenced by FNf and protease/antiprotease ratio

HIV/AIDS Research - Monocytes and CD4+ cell compartmentalization of HIV-1 occur in late infection

HIV/AIDS Research - NRTIs have different effects on resting cells infected with HIV

HIV/AIDS Research - Prostate is a reservoir for HIV-1

HIV/AIDS Research - Residual granulocytes likely source of alpha-defensins released into CD8 culture

HIV/AIDS Research - TRIM5alpha important natural barrier to cross-species retrovirus transmission

HIV/AIDS Therapy - Access to HAART increasing in Thailand

HIV/AIDS Therapy - Antifungal peptides inhibit HIV-1 reverse transcriptase

HIV/AIDS Therapy - DCP analogues are potent anti-HIV agents

HIV/AIDS Therapy - Guidelines detail provision of adherence support to individuals receiving HAART

HIV/AIDS Therapy - No clinically significant drug interactions observed with tenofovir DF

HIV/AIDS Therapy - RNA aptamers promising as anti-HIV therapeutic tool

HIV/AIDS Therapy - Serum-free IC50 values determined for lopinavir and ritonavir

HIV/AIDS Therapy - Single mutations at HR1 env region result in loss of susceptibility to ENF

HIV/AIDS Transmission - Street children/youth in Turkey misinformed about HIV transmission/protection

HIV/AIDS-Associated Disease - HIV-1 Tat increases adhesion of monocytes and T-cells to the endothelium

HIV/AIDS-Associated Tuberculosis - TB control/HIV care failures may contribute to continuing HIV-associated TB

HIV/AIDS-Related Drug Resistance - Novel method detects drug resistance of M-tropic and T-tropic HIV isolates

HIV/AIDS-Related Immunology - ILT2 expression may interfere with CD8 cell function by suppressing IFN-gamma

HIV/AIDS-Related Lipoatrophy - No change in mtDNA copy numbers in PBMCs in patients switched to abacavir

Hepatitis C Virus - Liver fibrosis predicts pegIFN/ribavirin outcome in HCV coinfection

Hepatitis C Virus Infection - Non-injecting sexual partners of HCV-infected persons at high risk for infection

Hepatitis C Virus Research - Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosornal degradation

Immunization - Combining treatment and testing of TB and HIV could save lives in Africa

Kaposi Sarcoma-Associated Herpesvirus - Recombinant KSHV with fluorescent protein enables study of lytic gene expression

Medical Marijuana - State medical marijuana applications open in October

Retrovirus Research - SIV Vpr/Vpx kill bystander noninfected CD4+ cells by induction of apoptosis

Sexually Transmitted Diseases - South Africa: Close connection between sexual assault and women's STI, HIV risk

Stem Cell Research - Economic study demonstrates Proposition 71 benefits to California's economy

Tuberculosis - Bovine tuberculosis is a new threat to Africa

Virology - Study of capsid proteins may shed light on retroviruses

Virology Vaccine - Dendritic cell vaccine protects against Friend retrovirus infection

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