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HIV/AIDS Epidemiology

Population genetics of HIV-1 group O estimates radiation from 1890 to 1940

Published in AIDS Weekly, October 18th, 2004

Population genetics of HIV-1 group O estimates radiation from 1890 to 1940.

"HIV-1 group O originated through cross-species transmission of SIV from chimpanzees to humans and has established a relatively low prevalence in Central Africa. Here, we infer the population genetics and epidemic history of HIV-1 group O from viral gene sequence data and evaluate the effect of variable evolutionary rates and recombination on our estimates," investigators in Belgium report.

"First, model selection tools were used to specify suitable evolutionary and coalescent models for HIV group O. Second," said P. Lemey and coworkers, "divergence times and population...

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