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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . November 15th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Research - Macaques infected with SIV chimera containing HIV-1 RT useful for NNRTI studies

HIV/AIDS Risk Factor - HSV-2 is key risk factor in promoting HIV transmission

HIV/AIDS Vertical Transmission - HIV subtype C preferentially transmitted in utero over subtypes A or D

HIV/AIDS Viral Load - HIV RNA levels differ by sex/risk group/age before ART initiation

HIV/AIDS-Related Genomics - (CCR)5-Delta32 polymorphism higher in HIV-negative exposed than HIV+ individuals

AIDS/HIV Therapy - Pharmacokinetic properties of reverse transcriptase inhibitors reviewed

AIDS/HIV Vaccine - Kinetics of virus-specific CD8+ T cells in HIV infection determined

AIDS/HIV Vaccine - Vaccine against HIV-1 B and E subtypes is safe and immunogenic

Antimicrobial Resistance - Antimicrobial resistance takes a large toll in developing countries

Aspergillosis - Researchers disable fungus by blocking its iron metabolism

Business Update - Biotech firm looking at possible expansion into Cambridge

Collaboration - Rapid test HIV-2 patent licensed from Bio-Rad

Disease Transmission - Healthcare workers in Africa aim to reduce HIV risk from breastfeeding

Drug Development - Pharma company completes humanization of 3G4 antibody

Drug Discovery - European regulatory application submitted for PROCLEIX ULTRIO Assay

Drug Resistance - Tool reveals molecular signature of cancer and HIV

Epidemiology - "Macro-level" risk factors for HIV transmission explored among black U.S. women

Finance - Biopharmaceutical company completes equity placement

Finance - Biotech completes new financing

HIV/AIDS - Diagnostics company luanches OraQuick ADVANCE Rapid HIV-1/2 Antibody Test

HIV/AIDS - Trial for HIV prevention gel commences

HIV/AIDS Coinfection - High HTLV-1 prevalence in immigrant male-to-female transsexual HIV+ sex workers

HIV/AIDS Drug Resistance - HIV-1 resistance to enfuvirtide characterized by very low genetic barrier

HIV/AIDS Exposure - Man charged with exposing women to HIV

HIV/AIDS Funding - Pennsylvania health secretary announces $1 million grant for HIV prevention

HIV/AIDS Funding - West Virginia to get $1 million in HUD funding for those with HIV or AIDS

HIV/AIDS Infection - Alcohol abuse associated with increased sexual risk for HIV infection in Africa

HIV/AIDS Pathogenesis - HIV-1 gp120 induces abnormal maturation of dendritic cells

HIV/AIDS Prevalence - HIV rate among Canada inmates is alarming

HIV/AIDS Prevention - Condoms remain a stigma among healthcare workers in Rwanda

HIV/AIDS Prevention - New Jersey Governor set to sign order allowing needle exchanges

HIV/AIDS Prevention - Prevention program demonstrates change in HIV/AIDS/STI knowledge in Sierra Leone

HIV/AIDS Prevention - Spread of HIV could slow if repeat testing is supported

HIV/AIDS Research - HIV-1 Tat regulates SOD2 basal promoter by altering Sp1/Sp3 binding activity

HIV/AIDS Research - HIV-1 compartmentalizes in diverse leukocyte populations during HAART

HIV/AIDS Research - Model developed to study function of HIV-infected monocyte-derived macrophages

HIV/AIDS Research - Novel assay identifies entry inhibitors that block HIV-1 gp120 binding to CCR5

HIV/AIDS Research - Proviral clone replicates the same as its parental HIV-1 group O isolate

HIV/AIDS Screening - Health Canada approves rapid HIV test

HIV/AIDS Screening - U.S. Health and Human Services, Ad Council launch HIV detection campaign

HIV/AIDS Survival - Former school chief, retired by AIDS, back into politics

HIV/AIDS Therapy - Antiretroviral drug HpAZT is less cytotoxic than AZT

HIV/AIDS Therapy - Development of HIV therapies GS 9005 and GS 7340 discontinued

HIV/AIDS Therapy - FDA grants traditional approval for fusion inhibitor for HIV treatment

HIV/AIDS Therapy - HIV-inhibitory cyclic depsipeptide isolated from marine sponge

HIV/AIDS Therapy - Infectious Diseases Institute opens in Uganda to care for people with HIV/AIDS

HIV/AIDS Therapy - Initial indinivir dose should based on patient sex and ritonavir intake

HIV/AIDS Therapy - K65R/Q151M mutations frequently selected during NRTI exposure in HIV-2 infection

HIV/AIDS Therapy - NNRT analog has novel mechanism for HIV RT inhibition

HIV/AIDS Therapy - Novel nonnucleoside HIV-1 RT inhibitors have minimal cytotoxicity

HIV/AIDS Therapy - Synthetic batzelladine analogues inhibit HIV-1 envelope-mediated fusion

HIV/AIDS Transmission - Myths dispelled concerning HIV transmission among conflict-affected populations

HIV/AIDS Trends - Health survey shows AIDS rate of 5.5% in Cameroon

HIV/AIDS-Coinfection - HIV-1 transactivated by Mycobacterium tuberculosis-infected macrophages

HIV/AIDS-Related Kaposi Sarcoma - Serologic response against ORF73 differs between HIV patients with/without KS

HIV/AIDS-Related Neurocognitive Impairment - Screening battery validated for HIV-related neurocognitive impairment

Hepatology - Portal CD4+ cells decline in hepatitis C virus HIV-coinfected patients

Immunology - HIV-1 envelope neutralizing antibody 2G12 analyzed

Infectious Disease - HIV/AIDS diagnostic kits bound for Malaysia

Infectious Disease - New institute helps patients and trains professionals in sub-Saharan Africa

Infectious Diseases - Institute to enhance health professional training in sub-Saharan Africa

Infectious Diseases - Malaria, TB, AIDS impose high economic burden in developing country households

Influenza Vaccine - Influenza vaccine enhances immune responses to SHIV antigens

Influenza Vaccine - PharmD comments on producing flu shots

Influenza Vaccine - Survey finds public not too worried about flu vaccine shortage

Influenza Vaccine - Trivalent influenza vaccine immunogenic in HIV-infected children

Malaria - Study shows Corixa's MPL adjuvant protected against uncomplicated malaria

Meningococcal Disease - Outbreak in France of N. meningitidis B:15:P1.12 belonging to sequence type 1403

Mergers & Acquisitions - Biotechnology companies revise merger terms

Neuropathy - PDGF-B chain protein expression is a forerunner of SHIV encephalitis

Obstetrics - Antiretroviral Pregnancy Registry monitoring and analysis plan described

Pneumonia - Cellular and Ab responses against C. pneumoniae may be mutually exclusive

Sexual Violence - War-driven rape fuels AIDS in the Democratic Republic of Congo

Tuberculosis - Doctors Without Borders calls for new drugs, tests for tuberculosis

Tuberculosis Therapy - Group calls for new treatments for TB

Virology - A novel DNA prime-boosting regimen produces antiviral immunity in study models

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