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HIV/AIDS-Related Mycobacterium

Mycobacterium avium complex infection in HIV infection rare in the era of HAART

Published in AIDS Weekly, November 22nd, 2004

Mycobacterium avium complex infection in HIV infection has dramatically decreased in the era of HAART.

"Disseminated Mycobacterium avium complex (MAC) infection is a common complication of late-stage HIV-1 infection. Since the advent of highly active antiretroviral therapy (HAART), the rate of MAC infection has declined substantially, but patients with low CD4 cell counts remain at risk.

"Among patients in the Johns Hopkins cohort with advanced HIV disease, the proportion developing MAC has fallen from 16% before 1996 to 4% after 1996, with a current rate of less than 1% per year," investigators in the United States report.

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