HIV/AIDS Research
Galantamine and nicotine inhibit HIV-1 gp120-induced microglial activation
Published in AIDS Weekly, December 13th, 2004
According to a study from the United States, "Chronic brain inflammation is the common final pathway in the majority of neurodegenerative diseases and central to this phenomenon is the immunological activation of brain mononuclear phagocyte cells, called microglia.
"This inflammatory mechanism is a central component of HIV-associated dementia (HAD). In the healthy state, there are endogenous signals from neurons and astrocytes, which limit excessive central nervous system (CNS) inflammation. However, the signals controlling this process have not been fully...
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Source: AIDS Weekly (2004-12-13)
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