HIV/AIDS Research
Temporal HIV-1 structures detected in samples separated by 22 months or more
Published in AIDS Weekly, December 13th, 2004
"A simple nonparameteric test for population structure was applied to temporally spaced samples of HIV-1 sequences from the gag-pol region within two chronically infected individuals. The results show that temporal structure can be detected for samples separated by about 22 months or more.
"The performance of the method, which was originally proposed to detect geographic structure, was tested for temporally spaced samples using neutral coalescent simulations," scientists in the United States report.
"Simulations showed that the method is robust to...
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Source: AIDS Weekly (2004-12-13)
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