Pediatric HIV/AIDS

African children with HIV would benefit from daily doses of cheap antibiotic

Published in AIDS Weekly, December 13th, 2004

Results of a randomized trial highlight how the low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries to help reduce illness and death from opportunistic infections such as pneumonia. The trial was stopped early when it became obvious that co-trimoxazole treatment nearly halved the mortality rate compared with placebo.

Antibiotic resistance limits the efficacy of drugs such as co-trimoxazole; no trials of this drug for HIV-infected adults or children have been done in areas with high levels of bacterial resistance to co-trimoxazole.

Diana Gibb (Medical Research Council, U.K.) and colleagues studied 541...

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Source: AIDS Weekly (2004-12-13)

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