HIV/AIDS & Tuberculosis
TB enhances efficient HIV transmission in lower respiratory tract mucosa
Published in AIDS Weekly, December 20th, 2004
"Nonsyncytium inducing, macrophage tropic HIV strains predominate in the course of active tuberculosis (TB). The present study assesses the expression of CCR5 in CD4+ T-lymphocytes from blood and bronchoalveolar lavage (BAL) of TB patients, non-TB lung disease controls and healthy controls.
"Memory (CD45RO), recently activated (CD69), proliferating (Ki67) CCR5+ or CCR3+ CD4+ T-lymphocytes were determined by multiparametric flow cytometry analysis," investigators in Italy report.
"Results show that BAL CD4+ T-lymphocytes expressing CCR5 or CCR3...
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Source: AIDS Weekly (2004-12-20)
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