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HIV/AIDS Research

Viremic HIV-1 infection associated with increased overall NK cell activity

Published in AIDS Weekly, December 20th, 2004

Viremic HIV-1 infection is associated with increased overall natural killer (NK) cell activity.

According to recent research from the United States, "NK cells are a subset of granular lymphocytes that are critical in the innate immune response to infection. These cells are capable of killing infected cells and secreting integral cytokines and chemokines.

"The role that this subset of cytolytic cells plays in HIV infection is not well understood. In this study, we dissected the function of NK cells in viremic and aviremic HIV-1-infected subjects, as well as HIV-1-negative control individuals."

"Despite reduced NK cell numbers in...

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