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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . January 10th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Drug Screening - Novel method screens HIV-1 RT inhibitors based on based on dock-MM-PB/GS

HIV/AIDS Research - Cross-species transmission of SIV realized

HIV/AIDS Vertical Transmission - HIV-1-infected breast milk cells associated with risk of vertical transmission

HIV/AIDS-Associated Dementia - Brain dopaminergic transporters decreased in HIV-associated dementia

Breast Cancer - Benefits of bisphosphonate clodronate for breast cancer presented at symposium

Business Update - Biotech company to expand manufacturing capacity with California facility

Business and Finance - Diagnostic test manufacturer announces positive first quarter results

Business and Finance - Drug development company announces first round of private financing

Clinical Trial - Immunology company provides clinical trials update

Drug Development - Cells expressing artificial complementary peptide inhibit HIV-1 infection

Drug Development - Hinnuliquinone inhibits HIV-1 protease

Drug Development - Mitochondrial membrane potential disruptor compounds attenuate Lv1 activity

Drug Development - Novel anti-HIV drug design strategy combats susceptibility to drug resistance

Drug Development - Novel strategy for small-molecule inhibition of viral fusion devised

Drug Development - Novel targets identified for HIV-1 treatment

Drug Development - Thermodynamics elucidated for next-generation protease inhibitor TMC114

Endocrinology - Mitochondrial insults harm metabolic function in HIV/HCV co-infected patients

Finance - HIV-focused biotech company, ACLARA announce stockholder approval of merger

Finance - Infectives-focused biotechnology company announces $20 million private placement

HIV Therapy - Data presented on HIV clinical trial progress

HIV/AIDS - Diagnostic test producer updates sales projection, live testing program

HIV/AIDS - Phase 2 trial of HIV maturation inhibitor drug announced

HIV/AIDS Cancer - Protease inhibitors increase risk of chemotherapy-induced neutropenia

HIV/AIDS Cognition - Interrater reliability modest for neurocognitive diagnoses in HIV infection

HIV/AIDS Comorbidity - Risk of tuberculosis doubles in first year of HIV infection

HIV/AIDS Epidemiology - AIDS may be managed as a security issue

HIV/AIDS Pathogenesis - APOBEC3G exploits RNA packaging to infiltrate HIV-1 particles

HIV/AIDS Pathogenesis - Amino-terminal region of HIV-1 nucleocapsid required for APOBEC3G packaging

HIV/AIDS Pathogenesis - Close relationship between HIV-1 phenotypic changes and HIV pathogenesis

HIV/AIDS Pathogenesis - Drug use increases risk of opportunistic infections among HIV-infected women

HIV/AIDS Prevention - Some drugstores refuse to sell syringes, despite laws

HIV/AIDS Research - AA insertions near gag cleavage sites restore activity of mutant protease

HIV/AIDS Research - Alpha-defensins inhibit/augment HIV replication by mechanisms that precede RT

HIV/AIDS Research - CD4 phosphorylation partially reverses Nef down-regulation of CD4

HIV/AIDS Research - Chloroquine prevents HIV-1 Tat from perturbing the cytokine balance

HIV/AIDS Research - Complete gene sequencing revealed novel IFN regulatory factor-1 polymorphisms

HIV/AIDS Research - Early plasmacytoid DC changes predict viral load rebound in primary infection

HIV/AIDS Research - Functionally impaired HIV CD8 cells show high affinity TCR-ligand interactions

HIV/AIDS Research - Gag influences HIV-1 species-specific tropism

HIV/AIDS Research - HIV-1 Vpr and Sp1 interplay modulates p21(WAF1) gene expression in astrocytes

HIV/AIDS Research - P-glycoprotein expression/genotype correlates with HIV-1 CXCR4 expression

HIV/AIDS Research - SIV Vif proteins are not effective inhibitors of human APOBEC3G or APOBEC3F

HIV/AIDS Research - Selection for cellular Ref1 activity loss releases HIV-1 from CypA dependence

HIV/AIDS Research - Ts1 infection of astrocytes accelerates cell death

HIV/AIDS Research - Viral/cellular protein interactions cause selective uptake of host ICAM-1 by HIV

HIV/AIDS Screening - MiraWell Rapid HIV test ranked No. 1 in China

HIV/AIDS Therapy - Assay enables simultaneous analysis of abacavir, 3TC, and AZT in tablets

HIV/AIDS Therapy - C-min/IC50 ratio predicts antiviral response during initial amprenavir-treatment

HIV/AIDS Therapy - Monomeric forms of peptide T analogs have conformational heterogeneity

HIV/AIDS Therapy - Statins reduce HIV-1 replication by preventing ICAM-1 and LFA-1 interactions

HIV/AIDS Treatment - AIDS group urges formation of blue ribbon commission to review drug research

HIV/AIDS Treatment - Drug makers putting complete AIDS treatment in one daily pill

HIV/AIDS Treatment - Foundation receives $1 million from WHO for fund of HIV treatment preparedness

HIV/AIDS Treatment - Pharmaceutical company reports on study of protease inhibitor for HIV infection

HIV/AIDS Vaccine - CXCR4-dependent infection of CD8+ lymphocytes by HIV isolate reported

HIV/AIDS Vaccine - Evolutionary dynamics of glycan shield of HIV during infection described

HIV/AIDS-Related Fertility - Medically assisted fertility is ethically acceptable in HIV-positive persons

HIV/AIDS-Related Psychosis - Atypical antipsychotic use associated with higher persistence in HIV infection

HIV/AIDS-Related Virology - Certain CTL epitopes subject to repeated positive selection in HIV infection

Hepatitis - Hepatitis experts join forces to educate public about disease and prevention

Hepatitis/HIV Coinfection - Study finds PegIntron and Rebetol achieved sustained virological response

Herpesvirus - HHV-8 can actively replicate in PBMCs

Medical Devices - New filter will improve speed, safety and economics of biopharma manufacturing

Patents - Company seeks patent on large-scale manufacturing process for high-purity DNA

Patents - Diagnostics testing provider receives patent for mitochondrial nucleic acid

Potable Water - Safe potable water provisions vary among hospitals caring for immunocompromised

SARS Vaccine - SARS vaccine induces SARS neutralizing antibodies

Sterilization - Terminal ethylene oxide disinfection inactivates viruses on muscle grafts

Tuberculosis - Novel antibiotic shows promise in shortening treatment of tuberculosis

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