Published in AIDS Weekly, January 17th, 2005
Today, TB is the leading cause of death in AIDS patients in high-burdened countries, mainly in sub-Saharan Africa. TB is particularly difficult to diagnose in AIDS patients because they often have few or no TB bacteria in their sputum; thus, the standard diagnostic procedure using microscopy is insensitive.
Classical culture methods for TB are more sensitive, but notoriously slow, typically requiring 21-42 days....
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