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Kaposi Sarcoma-Associated Herpesvirus

Fetal mesencyhmal stem cells susceptible to KSHV infection

Published in AIDS Weekly, January 24th, 2005

Fetal mesencyhmal stem cells are susceptible to Kaposi sarcoma-associated herpesvirus infection.

According investigators in the United States, "Recent reports link Kaposi sarcoma-associated herpesvirus (KSHV) infection of bone marrow cells to bone marrow failure and lymphoproliferative syndromes.

"The identity of the infected marrow cells, however, remains unclear. Other work has demonstrated that circulating mononuclear cells can harbor KSHV where its detection predicts the onset and severity of Kaposi sarcoma."

"In either setting," wrote C.H. Parsons and coworkers, "bone marrow precursors may serve as viral reservoirs. Since...

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