HIV/AIDS-Related Nutrition
Vitamins C and E protect against AZT-induced oxidative stress
Published in AIDS Weekly, January 24th, 2005
According to a study from Spain, "AZT (zidovudine) is a potent inhibitor of HIV replication and a major antiretroviral drug used for AIDS treatment. A major limitation in the use of AZT is the occurrence of severe side effects.
"The aim of this work was to test whether AZT causes oxidative damage to heart mitochondria and whether this can be prevented by supranutritional doses of antioxidant vitamins."
"An experimental animal model was used in which mice were treated with AZT for 35 days (10 mg/kg/day) in drinking water," said J.G. De la Asuncion and coworkers.
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Source: AIDS Weekly (2005-01-24)
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