Published in AIDS Weekly, February 7th, 2005
"An intranasal DNA vaccine prime followed by a gp41 peptide booster immunization was compared with gp41 peptide and control immunizations. Serum HIV-1-specific IgG and IgA as well as IgA in feces and vaginal and lung secretions were detected after immunizations. Long-term humoral immunity was studied for up to 12 months after the booster immunization by testing the presence of HIV-1 gp41- and CCR5-specific antibodies and IgG/IgA-secreting B lymphocytes in spleen and regional lymph nodes in immunized mice,"...
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