HIV/AIDS Pathogenesis
Improved control of HIV-2 infection may relate to contribution of CD4 response
Published in AIDS Weekly, February 21st, 2005
According to recent research from the United States, "Human immunodeficiency virus type 2 (HIV-2) infection is typically less virulent than HIV-1 infection, which may permit the host to mount more effective, sustained T-cell immunity.
"We investigated antiviral gamma interferon-secreting T-cell responses by an ex vivo Elispot assay in 68 HIV-1- and 55 HIV-2-infected Senegalese patients to determine if differences relate to more efficient HIV-2 control."
"Homologous HIV-specific T cells were detected in similar frequencies (79% versus 76%,...
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Source: AIDS Weekly (2005-02-21)
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