HIV/AIDS Therapy
Curcumin inhibits acetylation of HIV Tat by p300 as well as virus proliferation
Published in AIDS Weekly, February 21st, 2005
According to published research from India, "Acetylation of histones and non-histone proteins is an important post-translational modification involved in the regulation of gene expression in eukaryotes and all viral DNA that integrates into the human genome (e.g., the human immunodeficiency virus).
"Dysfunction of histone acetyltransferases (HATs) is often associated with the manifestation of several diseases. In this respect, HATs are the new potential targets for the design of therapeutics."
"In this study," K. Balasubramanyam and coworkers said,...
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Source: AIDS Weekly (2005-02-21)
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