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HIV/AIDS Transmission

Micronutrient supplementation increases genital tract shedding of HIV-1 in women

Published in AIDS Weekly, March 14th, 2005

Micronutrient supplementation increases genital tract shedding of HIV-1 in women.

"To test the hypothesis that micronutrient supplementation decreases genital HIV-1 shedding, a double-blind, randomized, placebo-controlled trial of 6 weeks of multivitamin plus selenium supplementation vs. placebo was conducted among 400 HIV-1-seropositive, nonpregnant, antiretroviral-naive women in Mombasa, Kenya.

Primary outcome measures included cervical and vaginal shedding of HIV-1-infected cells and RNA. Secondary outcomes included plasma viral load and CD4 count," investigators in the United States report.

"Surprisingly," said R.S. McClelland...

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