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HIV/AIDS Vaccine

HIV genomic RNA sequences in female genital tract and blood reported

Published in AIDS Weekly, March 28th, 2005

Researchers report human immunodeficiency virus type 1 genomic RNA sequences in the female genital tract and blood in a recent issue of the Journal of Virology.

"Investigation of human immunodeficiency virus type 1 (HIV-1) in the genital tract of women is crucial to the development of vaccines and therapies. Previous analyses of HIV-1 in various anatomic sites have documented compartmentalization, with viral sequences from each location that were distinct yet phylogenetically related. Full-length RNA genomes derived from different compartments in the same individual, however, have not yet been studied. Furthermore, although there is evidence that intrapatient...

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