AIDS Weekly

HIV/AIDS Drug Development - PNA-transportan conjugate targeted to HIV-1 TAR is antiviral and virucidal

HIV/AIDS Infection - Amphotericin-B reactivates latent HIV-1 infection

HIV/AIDS Lipodystrophy - VLDL elevation in early HAART therapy caused by impaired VLDL clearance

HIV/AIDS Therapy - 20 mg/kg of amprenavir twice daily is safe for HIV-infected children

HIV/AIDS Therapy - IL-16 levels increase after structured intermittent HAART interruption

Awards - GlaxoSmithKline CEO Jean-Pierre Garnier gets Global Business Leadership award

Business Update - Medical services company extends distribution over 10 Chinese provinces

Cancer Drugs - RLIP76 transported vinorelbine and mediated drug resistance in NSCLC

Candidiasis - Discovery may lead to better antifungal drug

Clinical Trials - Enrollment of phase 2 clinical trial of antibody for treatment of HIV complete

Collaborations - Agreement signed for OraQuick HIV test

Finance - Genetics-focused company reports fourth quarter, year end 2004 financial results

HIV/AIDS - Styrylquinolines are synergistic with other antiretroviral agents

HIV/AIDS Diagnosis - Uncertainties of incidence estimates of HIV/AIDS diagnoses adjusted

HIV/AIDS Drug Development - Anti-HIV-1 compounds separated via capillary zone electrophoresis

HIV/AIDS Drug Development - Plant extracts have anti-HIV activity

HIV/AIDS Drug Discovery - HIV-1 integrase inhibitors identified using 3D pharmacophore-guided database

HIV/AIDS Drug Resistance - Drug-resistant HIV-1 genotypes detected only in subjects infected after 2000

HIV/AIDS Drug Resistance - HIV-1 Vif changes associated with development of protease inhibitor resistance

HIV/AIDS Education - Cognitive intervention method reduces HIV/AIDS discriminatory attitudes

HIV/AIDS Epidemiology - HIV-1 spread through six transmission lines in the U.K.

HIV/AIDS Healthcare - Unmet dental needs perceived to be associated with socioeconomics in HIV/AIDS

HIV/AIDS MALT Lymphoma - HIV+ MALT lymphoma remission induced by HAART alone

HIV/AIDS Pathogenesis - APOBEC3G polymorphisms not associated with HIV disease progression

HIV/AIDS Pathogenesis - C-terminal domain of HIV-1 integrase is a DNA-binding domain

HIV/AIDS Pathogenesis - Cytoplasmic tail slows HIV-1 Env folding from late prebundle into 6-helix bundle

HIV/AIDS Pathogenesis - Late stage R5 HIV-1 infection induces cytokine and CCR5 expression

HIV/AIDS Pathogenesis - M-tropic HIV-1 activation increases virus load in intestinal mucosa

HIV/AIDS Pathogenesis - Separate HIV Nef domains are required to affect MHC-1 and CD4 cells

HIV/AIDS Pathogenesis - Vpr enhances RANKL production via glucocorticoid receptor activity potentiation

HIV/AIDS Prevention - Appropriate HIV education maximizes acceptance of antenatal HIV antibody test

HIV/AIDS Prevention - Manufacturing company wins government tender for rapid HIV test in China

HIV/AIDS Prevention - Predictors of condom use determined among HIV-positive patients in South Africa

HIV/AIDS Prognosis - Survival prognostic factors differ by CD4 count among IVDU pre/post HAART era

HIV/AIDS Research - CD4+ cell response differs between HIV-exposed seronegative and HIV+ women

HIV/AIDS Research - MLV RNase H primer grip is an important determinant of fidelity of DNA synthesis

HIV/AIDS Research - Tat methylation by PRMT6 regulates HIV-1 gene expression

HIV/AIDS Screening - Molecular diagnostics company reports detection of HIV-DNA AIDS patients' urine

HIV/AIDS Screening - Urgent care center-based routine HIV screening programs are effective