HIV/AIDS Pathogenesis
Recent findings in HIV/AIDS pathogenesis provide new insights
Published in AIDS Weekly, April 18th, 2005
Study 1: Separate HIV Nef domains are required to affect MHC-1 and CD4 cells.
"Human immunodeficiency virus type 1 (HIV-1) Nef is a critical protein that is necessary for HIV pathogenesis. Its roles include the disruption of major histocompatibility complex class I (MHC-I) and CD4 trafficking to promote immune evasion and viral spread.
"Mutational analyses have revealed that separate domains of Nef are required to affect these two molecules," investigators in the United States report.
"To further elucidate how Nef disrupts MHC-I...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
Source: AIDS Weekly (2005-04-18)
More Articles from AIDS Weekly
- HIV/AIDS Drug Development
Pyridine N-oxide derivatives protects against HIV-induced CD4 cell destruction - HIV/AIDS Pathogenesis
Endocytosis contributes to productive HIV entry - HIV/AIDS Therapy
CSF HIV is an accessible surrogate for HIV virions in brain - HIV/AIDS Therapy
IL-7 induces latent HIV-1 cellular reservoirs of infected individuals on HAART - HIV/AIDS-Related Metabolic Syndrome
Lipid-lowering drugs may cause pharmacokinetic interactions with antiretrovirals - Allergy & Immunology
HIV's early victims revealed - More from this issue of AIDS Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
