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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . May 2nd, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Diagnostics - NucliSens EasyQ correlates with Roche Amplicor in monitoring HIV-1 RNA in Africa

HIV/AIDS Diagnostics - Sensitive PCR estimates HIV-1 in CD4+ cells in patients responding to HAART

HIV/AIDS Drug Development - CCR5 antagonist suppresses replication/CPE in HIV-infected mouse model

HIV/AIDS HAART - High blood lipids observed with PIs increase 10-year coronary risk

HIV/AIDS Pathogenesis - Unintegrated HIV-1 reservoir in recently infected resting CD4+ cells very labile

AIDS Research - Initiating ART in primary SIV may lead to mucosal immune system restoration

AIDS Therapies - UN says anti-AIDS gel for women isn't far off

AIDS-Related Dementia - Tat-induced CCL2 secretion may be early signal during NeuroAIDS

Antiviral Drug Development - Understanding viral life cycles crucial to exploit antiviral strategies

Avian Influenza - Germicidal product passes efficacy test for eradicating bird flu virus

Business Update - Company focused on HIV prevention receives grant for product development

HIV/AIDS Vaccines - Reports add new data to HIV/AIDS vaccines research

Business Update - Nanobiotechnology company changes name and enters new markets

Cell Biology - Scientists reveal shape of a protein that helps retroviruses break into cells

Contraceptive Microbicide - Contraceptive microbicide nonoxynol-9 has deleterious effects on endometrium

DNA Research - Italian patent application filed on transrenal DNA technology to detect HIV, TB

Diet & Nutrition - Elemental diet improves nutritional recovery from diarrhea/malnutrition

Drug Development - CEL-1000 peptide effective against viral encephalitis in mice

Environmental Health - Survey of perioperative RNs shows double gloving occurs 42% as much as it should

Epidemiology - Women, children in northern Uganda receiving assistance from NGO

Finance - Biopharmaceutical company updates its 2005 revenue guidance

HIV Transmission - HIV positive women in South Africa still facing stigma, ostracism

HIV-2 Epidemiology - SIVsm strains isolated from Sierra Leone bush meat highly divergent from HIV-2

HIV/AIDS & Syphilis Coinfection - Seronegative syphilis in HIV patient tests positive by dark field examination

HIV/AIDS Diagnostics - Early response to antiretroviral treatment predicts long-term response

HIV/AIDS Drug Interactions - Antiretrovirals often interact with medications for OIs and primary care

HIV/AIDS Drug Resistance - Recent findings in HIV/AIDS drug resistance described

HIV/AIDS Epidemic - Assay screens HIV-1 in epidemics characterized by mono/dual clade predominance

HIV/AIDS Healthcare - Treatment-seeking behavior same in HIV/AIDS orphans/nonorphans in Kampala

HIV/AIDS Pathogenesis - APOBEC3G antiviral function can dissociate from cytidine deaminase activity

HIV/AIDS Pathogenesis - HIV-1 catalytic core domain residues important for HIV-1 replication/integration

HIV/AIDS Pathogenesis - HIV-1 clade promoters strongly influence replication spatial/temporal dynamics

HIV/AIDS Pathogenesis - HIV-1-specific CD4+ cell turnover and activation increase upon viral rebound

HIV/AIDS Pathogenesis - POSH is essential for HIV-1 production

HIV/AIDS Pediatrics - Infants are increasingly exposed antiretrovirals even from conception

HIV/AIDS Prevention - Cost is barrier to receive HIV testing as part of premarital counseling in China

HIV/AIDS Prevention - Foundation, J&J to initiate programs to prevent PMTCT of HIV in 7 countries

HIV/AIDS Research - "Preloaded" natural killer cells efficiently lyse HIV-infected target cells

HIV/AIDS Research - Quantitation of RT-PCR defective/ecotropic viruses in murine AIDS

HIV/AIDS Risk Behavior - Puerto Rican crack users in Puerto Rico have riskier sex than those in New York

HIV/AIDS Therapy - Chronic viral hepatitis alters the pharmacokinetics of antiretroviral therapy

HIV/AIDS Therapy - Lethal mutagenesis may be used to extinguish HIV infection

HIV/AIDS Therapy - NNRTIs and RNase H inhibitors given in same HAART regimen may be beneficial

HIV/AIDS Therapy - Older antiretroviral strategies show renewed interest

HIV/AIDS Therapy - UK government lauded for microbicide development support

HIV/AIDS Vaccine - CTL programming allows soluble antigen to generate secondary CTL

HIV/AIDS Vaccine - Data on DNA-binding protein to correct human genes published online in 'Nature'

HIV/AIDS Vaccine - HLA peptide processing by dendritic cells from HIV+ patients examined

HIV/AIDS Vaccine - Immune-based biopharmaceutical company auditors note going-concern qualification

HIV/AIDS Vaccine - Segments of consecutive AA residues of HIV gp120 proposed as vaccine candidates

HIV/AIDS Vaccine - Vaccine-elicited antibodies reduce viremia in SIV-challenged macaques

HIV/AIDS Vaccines - Findings advance knowledge in HIV/AIDS vaccines research

HIV/AIDS-Associated Emphysema - AIDS-associated emphysema due in part to HIV-1 infection of alveolar macrophages

HIV/AIDS-Epidemiology - High HSV-2/HHV-8 in remote area belies behavior that may facilitate HIV spread

HIV/AIDS-Related Hodgkin Lymphoma - LMP-1 deletion mutants highly associated with HIV-related Hodgkin's lymphoma

Hematology - New findings in hematology described

Hepatitis B Virus - Biotech company granted CE mark for two diagnostic tests

Human Papillomavirus - Investigational HPV vaccine reduced infection and disease in study

Human Papillomavirus-Associated Cancer - HPV strongly associated with several cancers independent of HIV infection

Legal Issues - Gen-Probe prevails in arbitration concerning viral diagnostics collaboration

Personnel - Vaccines company announces addition to board of directors

Simian T-Cell Lymphotropic Virus Type 1 - Africa is origin of Tulane primate center STLV-1 sooty mangabey strain

Tuberculosis - Two sputum specimens adequate for pulmonary tuberculosis diagnosis

Virology - Challenges of treating HIV, TB concurrently examined in study

Virology - DNA flap position does not influence lentiviral vector transduction

Virology - Researchers' work adds to virology body of knowledge

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