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HIV/AIDS Surveillance

"Detuned" HIV immunoassay detects infections missed by surveillance methods

Published in AIDS Weekly, May 23rd, 2005

A "detuned" HIV immunoassay detects infections missed by surveillance methods.

"Between 1999 and 2000, new diagnoses of HIV in Victoria (Australia) rose by 41%, from 140 to 197. In this time period, sera from new HIV diagnoses were tested using the Organon Teknika 'detuned' enzyme immunoassay (EIA).

"We compared the results of the detuned EIA with incident infections defined by surveillance (on the basis of a previous negative or indeterminate HIV test and/or a seroconversion illness within the 12 months preceding HIV diagnosis)," investigators in Australia report.

"Of 317 specimens," said R.J. Guy and coworkers at the Macfarlane...

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