Published in AIDS Weekly, June 27th, 2005
Study 1: A prime-double boost immunization strategy elicited long-lived multi-isotype anti-HIV antibody responses.
"Despite decades of work, an effective HIV vaccine remains elusive. In an effort to elicit protective immunity, investigators have sought to define vaccines able to elicit durable HIV-specific B-cell and T-cell activities. Additionally, vaccines are sought which can induce antibodies of a variety of isotypes, as each isotype possesses unique attributes in terms of opsonization, Fc receptor binding capacity, complement fixation and location,"...
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Source: AIDS Weekly (2005-06-27)
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