HIV/AIDS Vaccines
Researchers detail new studies and findings in the area of HIV/AIDS vaccines
Published in AIDS Weekly, July 4th, 2005
Study 1: Dynamic immune responses maintain cytotoxic T lymphocyte (CTL) epitope mutations in transmitted simian immunodeficiency virus (SIV) variants.
"Viral escape from cytotoxic T lymphocytes (CTLs) can undermine immune control of human immunodeficiency virus 1. It is therefore important to assess the stability of viral mutations in CTL epitopes after transmission to naive hosts. Here we demonstrate the persistence of mutations in a dominant CTL epitope after transmission of simian immunodeficiency virus variants to major histocompatibility...
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Source: AIDS Weekly (2005-07-04)
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