Virology
HIV may produce inhibitory microRNAs that block protein production
Published in AIDS Weekly, July 11th, 2005
"It is well-known that human immunodeficiency virus type 1 (HIV-1) infection results in a gradual decline of the CD4+ T-lymphocytes, but the underlying mechanism of this decline is not completely understood. Research has shown that HIV-1 infection of CD4+ T cells results in decreased CD28 expression, but the mechanism of this repression is unknown," researchers in the United States report.
"There is also substantial evidence demonstrating regulatory involvement of microRNA (miRNA) during protein expression in plants and some animals, and reports have recently been published...
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Source: AIDS Weekly (2005-07-11)
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