HIV/AIDS Coinfection
HIV-specific cytolysis/increased IL-10 associated w/ S. mansoni coinfection
Published in AIDS Weekly, July 18th, 2005
According to recent research published in the Journal of Immunology, "Impaired virus-specific immune responses have previously been observed with Schistosoma mansoni coinfection. We characterized Gag-specific responses in HIV-1-positive Ugandans with and without S. mansoni coinfection."
"We observed no significant difference in the frequency of IFN-gamma CD8+ T cells between the two groups. Interestingly, expression of CD107, a marker for cytolytic activity, was significantly lower in volunteers with S. mansoni...
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Source: AIDS Weekly (2005-07-18)
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