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HIV/AIDS Drug Development

Ginsenosides block ritonavir-induced vascular dysfunction of coronary arteries

Published in AIDS Weekly, July 18th, 2005

Ginsenosides block ritonavir-induced vascular dysfunction of coronary arteries.

According to recent research published in the American Journal of Physiology - Heart and Circulatory Physiology, "Human immunodeficiency virus (HIV) protease inhibitor ritonavir (RTV) may induce vascular dysfunction through oxidative stress. Ginsenosides have been shown to have potential benefits on the cardiovascular system through diverse mechanisms, including antioxidative property."

"The objective of this study was to determine whether ginsenosides could prevent coronary arteries from RTV-induced dysfunction. Porcine coronary artery rings were incubated with...

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