HIV/AIDS Prognostics
HIV-1-specific CD4 cell responses+IgG2 Ab predicts long-term nonprogression
Published in AIDS Weekly, July 18th, 2005
"Strong T cell and antibody responses to human immunodeficiency virus (HIV), low virus production, and some genetic traits have been individually associated with nonprogression of HIV infection, but the best correlate with protection against disease progression remains unknown.
"We prospectively followed 66 untreated long-term nonprogressors and analyzed relationships between HIV-1-specific CD4 T helper (Th) 1 and CD8 T cell responses and HIV-1-specific antibodies, HIV-1 RNA and proviral DNA loads, host genes, and CD4 Th1 cell counts at entry into the study and 4...
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Source: AIDS Weekly (2005-07-18)
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