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Companies announce antibody drug conjugate collaboration

Published in AIDS Weekly, July 18th, 2005

Seattle Genetics, Inc. (SGEN) and PSMA Development Company LLC (PDC), a joint venture between Progenics Pharmaceuticals, Inc. (PGNX) and Cytogen Corporation (CYTO), announced that Seattle Genetics has licensed its proprietary antibody-drug conjugate (ADC) technology to PDC.

The license provides PDC with rights to utilize the ADC technology to link cell-killing drug payloads to PDC's fully human monoclonal antibodies that target prostate-specific membrane antigen (PSMA), which is highly expressed on both primary and metastatic prostate cancer cells.

PSMA is a protein abundantly expressed on the surface of prostate cancer cells with an increased...

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