Susan Hasty, Publisher
Table of Contents . . . August 1st, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in AIDS Weekly | Other Publications
HIV/AIDS Drug Adherence - Stavudine adherence improves with switch to once-daily dosing
HIV/AIDS Pathogenesis - HIV Nef protein promotes survival of infected cells
HIV/AIDS Prognostics - CD4:CD8 ratio or CD4 percentage determines risk of progression with HAART
HIV/AIDS Prognostics - CX(3)CR1 polymorphisms predict HIV-1 disease progression in children
Viral Load - Gender difference in HIV-1 RNA viral loads dependent on CD4 cell count
Animal Studies - Single-cycle SIV immunization reduces viral loads after SIVmac 239 challenge
Business Update - Biotechnology company broadens supply agreement with healthcare corporation
Business Update - U.K. investment firm reiterates buy recommendation on pharmaceuticals company
Cachexia - U.S. FDA approves Megace ES for weight loss in AIDS patients
Chagas Disease - Researchers identify protein machinery of Chagas disease parasite
HIV/AIDS Pathogenesis - Reports describe recent advances in HIV/AIDS pathogenesis research
Collaborations - Global team formed to develop antidiarrhea compound
Diagnositcs - Diagnostic test kits receive approval in additional countries
Diagnostics - CE Mark certification granted for HIV-1 real-time PCR viral load test
Diagnostics - Company announces distribution agreements in eight African countries
Drug Abuse - Syringe exchange programs offer good vehicle for public health messages
Drug Development - Pharma company provides development pipeline update
HIV/AIDS Pathogenesis - Research add new data to HIV/AIDS pathogenesis body of knowledge
Drug Development - U.S. FDA issues approval for Aurobindo for AIDS
Drug Development - U.S. FDA issues final approval for Stavudine for AIDS
End Stage Kidney Disease - Hepatitis B vaccine raises antibody in HIV-infected hemodialysis patients
Finance - NIAID funds Center for HIV/AIDS Vaccine Immunology
Generic Drugs - Agency tentatively approves another first-time generic AIDS drug
HIV Transmission - Secretive bisexual activity does not translate to HIV risk
HIV/AIDS Vaccines - Recent findings in HIV/AIDS vaccines described
HIV/AIDS & Tuberculosis Coinfection - HIV infection may not be associated with drug resistant tuberculosis
HIV/AIDS Coinfection - Asymptomatic syphilis detected more frequently in HIV patients
HIV/AIDS Diagnostics - MRSI used to assess neuronal function in HIV-1-associated dementia
HIV/AIDS Drug Development - Directed evolution creates new PDZ domains for HIV protease activity detection
HIV/AIDS Drug Development - Human cell factor(s) inhibit HIV reverse transcriptase
HIV/AIDS Drug Development - Oximinoarylsulfonamides inhibit HIV protease
HIV/AIDS Vaccines - Recent findings in HIV/AIDS vaccines provide new insights
HIV/AIDS Drug Development - South African medicinal plant extracts inhibit HIV-1 RT/integrase
HIV/AIDS Drug Resistance - FHIV-1 L89M mutation is high genetic barrier to accumulation of L90M mutations
HIV/AIDS Drug Side Effect - HIV medications impact speech and hearing
HIV/AIDS Drug Side Effect - High OPG levels may protect against bone resorption in HIV patients on HAART
HIV/AIDS Economics - Economic implications of AIDS may be serious for India in the future
HIV/AIDS Epidemiology - High HIV transmission rates in Africa due to high rates of other untreated STIs
HIV/AIDS Vaccines - Research in HIV/AIDS vaccines provides new insights
HIV/AIDS HAART - Abacavir + efavirenz effective PI alternative in heavily pretreated HIV patients
HIV/AIDS HAART - HAART initiation will alter the biology and evolution of HIV/AIDS in India
HIV/AIDS HAART - Improved response to HAART may also be attributable to adherence/tolerability
HIV/AIDS HAART - Low-cost assays can monitor HAART patients in developing countries
HIV/AIDS Heart Disease - Ritonavir impairs vasomotor function/reduces coronary artery eNOS expression
HIV/AIDS Pathogenesis - APOBEC3G ubiquitination by HIV-1 Vif-BC-Cul5 is essential for Vif function
HIV/AIDS Pathogenesis - Data advance knowledge in HIV/AIDS pathogenesis research
HIV/AIDS Pathogenesis - Fitness differences of 2 HIV-1 isolates related to cell binding/entry efficacy
HIV/AIDS Pathogenesis - HIV Nef establishes superinfection immunity by downregulating CCR5 and CD4
HIV/AIDS Pathogenesis - HIV without polypurine tract mutations can replicate at low level
HIV/AIDS Pathogenesis - HIV-1 Tat concomitantly downregulates caspase-10/upregulates c-FLIP in T cells
HIV/AIDS Pathogenesis - Mutant Vif proteins incapable of modulating viral infectivity
HIV/AIDS Postexposure Prophylaxis - TDF-3TC-d4T most tolerated regimen for nonoccupational postexposure prophylaxis
HIV/AIDS Prevention - New findings in HIV/AIDS prevention described
HIV/AIDS Prevention - U.S. FDA approves new anti-HIV drug Aptivus for use in combination therapy
HIV/AIDS Prognosis - Baseline CD4 count strongest predictor of short-term disease progression in Asia
HIV/AIDS Prognostics - CD4+ T cell count monitors HIV progression & antiretroviral therapy
HIV/AIDS Research - D. melanogaster complementary system to study HIV-1-related genes/proteins
HIV/AIDS Screening - Rapid HIV testing strategies feasible in under equipped laboratories
HIV/AIDS Testing - Diagnostic test developer expands HIV/AIDS testing in Latin America
HIV/AIDS Testing - Maker of HIV rapid tests announces donation valued at $1,000,000
HIV/AIDS Therapy - Phase 3 trial of ThGRF for treating HIV-associated lipodystrophy launched
HIV/AIDS Vaccine - Ulex europaeus agglutinin targets mucosal vaccine against HIV-1 envelope
HIV/AIDS Vaccine - HIV gp120 immunogenicity enhanced when combined with recombinant DNA priming
HIV/AIDS Vaccine - HIV-1-specific CD8+ T cell epitopes presented by HLA-A*2601 characterized
HIV/AIDS Vaccine - Vaccine-induced CD4 T cells lose reactivity after SIV/HIV challenge
HIV/AIDS Vaccines - New findings in the area of HIV/AIDS vaccines detailed
HIV/AIDS-Related Dementia - AIDS dementia complex remains a problem in the era of HAART
HIV/AIDS-Related Drug Side Effect - Ritonavir affects basal and catecholamine-stimulated lipolysis in adipocytes
HIV/AIDS-Related Lipodystrophy - Intermittent HAART may reduce incidence or slow development of lipoatrophy
HIV/AIDS-Related Mental Health - Trauma and stress in HIV patients accounted for by increases in PTSD symptoms
HIV/AIDS-Related Nutrition - Reduced micronutrient intake accentuates premature death in murine AIDS
Kaposi Sarcoma-Related Herpesvirus - KSHV lytic replication cycle promotes downregulation of cell-surface CD1d
Legal Issues - U.S. trade representative's office urged to condemn Brazilian TRIPS threat
Papillomavirus - DNA methylation may force HPVs into latency with repressed transcription
Patents - Gene therapy company granted patents for vectors derived from lentiviruses
Personnel - TB partnership names director of policy
Philanthropy - ExxonMobil announces new community investment initiative
Reproductive Medicine - Success factors for semen cleansing in men coinfected with HIV and HCV vary
Respiratory Syncytial Virus - Pharma company signs license agreement with Arrow Therapuetics
Sexually Transmitted Disease - Cytokine profile shifts in HIV-1/HIV-2/dual infection with disease progression
Toxoplasma Gondii - Aureobasidin A blocks T. gondii replication w/o affecting host metabolism
Transplant Medicine - Mitochondrial toxicity hampers liver transplants in HIV-HCV coinfected patients
Tuberculosis Prevention - Preventive TB therapy in HIV-infected persons can impact morbidity & mortality
Vaccine Development - Life science company awarded global license for Parvovirus B19 vaccine
Virology - Hepatitis C coinfection boosts liver failure risk in patients with HIV
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