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HIV/AIDS HAART

Risk of triple-class antiretroviral drug failure declining in Denmark

Published in AIDS Weekly, August 8th, 2005

The risk of triple-class antiretroviral drug failure is declining in Denmark.

"To analyze the incidence, prevalence, and predictors for development of triple-class antiretroviral drug failure (TCF) in individuals infected with HIV," a population based "observational cohort study from January 1, 1995 to December 31, 2003" focused "on all 2722 recipients of highly active antiretroviral therapy (HAART) in Denmark."

"We used person-years analysis, Kaplan-Meier survival curves and Cox regression analysis. TCF was defined as a minimum of 120 days with viral load >1000 copies/ml on treatment with each of the three major drug classes," scientists writing...

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