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Virology

HIV values remain stable in hepatitis C coinfected patients on peginterferon

Published in AIDS Weekly, August 8th, 2005

HIV values remain stable in hepatitis C coinfected patients on peginterferon.

"We evaluated the safety and efficacy of peginterferon alpha-2a (pegIFN alpha-2a), with or without ribavirin, in 154 hepatitis C virus/human immunodeficiency virus (HCV/HIV) coinfected patients. All received pegIFN alpha-2a (180 mcg/week) for 12 weeks, with those achieving an early virologic response (EVR) continued on monotherapy through week 48," researchers in the United States report.

"Patients without an EVR were randomized at week 14 to also receive ribavirin (800 mg/day) or placebo through week 48. Patients with detectable HCV RNA at week 24 were discontinued,"...

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