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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . August 22nd, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Coinfection -  Neisseria gonorrhoeae enhances infection of dendritic cells by HIV-1

HIV/AIDS Needlestick Injury - Postexposure practice inadequate in medical students with needlestick injury

HIV/AIDS Pathogenesis - Cultured myeloid dendritic cells from HIV patients fail to differentiate

HIV/AIDS Perinatal Transmission - Nevirapine resistance after single NVP dose higher in women with HIV-1 subtype C

HIV/AIDS Transmission - Incorporation of ABO antigens by HIV-1 may affect viral transmission

Awards - Stephen C. Harrison wins Bristol-Myers Squibb infectious diseases research award

Business & Finance - Diagnostic tests company projects first quarter profit

Clinical Trials - Eight-week doxycycline course safe/effective for lymphatic filariasis

Clinical Trials - Recombinant protein HIV vaccine candidate to be tested in clinical trials

Finance - Biotechnology company announces second quarter 2005 financial results

Finance - Health products company reports second quarter results

HIV/AIDS Vaccines - New research in the area of HIV/AIDS vaccines detailed

Finance - Infections-focused biotechnology company reports second quarter 2005 results

Finance - Molecular medicines company reports second quarter 2005 financial results

Finance - Viread maker reports Q2 revenues of $495.3 million, up 55%

Genital Herpesvirus Infection - Topical microbicides needed for prevention of genital herpes infections

HIV/AIDS - Pharma firm reaches agreement with Brazilian government for AIDS drug

HIV/AIDS Diagnosis - Ten-minute, U.S. FDA-approved HIV test developed

HIV/AIDS Vaccines - Researchers detail new studies and findings in the area of HIV/AIDS vaccines

HIV/AIDS Disease Progression Risk Factors - Pattern/type of non-injection drug use associated with progression to AIDS

HIV/AIDS Drug Development - Amino acid Asn136 of HIV-1 RT enables rational design of RT inhibitors

HIV/AIDS Drug Development - Mesuol inhibits HIV-1 replication by targeting NF-kappa B pathway

HIV/AIDS Drug Development - Short hairpin RNAs targeting human cyclin T1 suppresses HIV-1 replication

HIV/AIDS Education - Low health literacy associated with HIV test acceptance

HIV/AIDS Education - Peer education or lecture increases HIV/AIDS knowledge among college students

HIV/AIDS Vaccines - Researchers provide details of new studies and findings in the area of HIV/AIDS vaccines

HIV/AIDS Epidemiology - Differential susceptibility important determinant of steady-state HIV prevalence

HIV/AIDS Epidemiology - Majority of HIV-1 cases among Africa-born patients in Minnesota are non-B

HIV/AIDS Opportunistic Infection - Calciviruses may be important opportunistic pathogen in HIV-infected children

HIV/AIDS Pathogenesis - CD4+ cells have impaired base excision repair/oxidative base lesion accumulation

HIV/AIDS Pathogenesis - HIV Tat induction of IL-10 dysregulation associated with PKR activation

HIV/AIDS Pathogenesis - Infectivity of CXCR4-using isolates depends on CD4 expression

HIV/AIDS Vaccines - Researchers publish new studies and findings in the area of HIV/AIDS vaccines

HIV/AIDS Pathogenesis - Peripheral S-phase T cells in HIV disease have a central memory phenotype

HIV/AIDS Pathogenesis - Reports describe recent advances in HIV/AIDS pathogenesis research

HIV/AIDS Pharmacokinetics - Body weight/female gender affects enfuvirtide clearance but not safety/efficacy

HIV/AIDS Prevention - HIV prevention program increases willingness to reduce adolescent risk behaviors

HIV/AIDS Prognostic Marker - Early HIV-1 PBMC DNA level predicts disease progression independent of RNA/CD4+

HIV/AIDS Research - CHMP offers positive opinion in Europe for Tipranavir

HIV/AIDS Research - Enrollment complete in phase 1 trial of PRO 140

HIV/AIDS Research - Phase 1/2a study results indicate maraviroc is well tolerated

HIV/AIDS Research - Phase IIb sudy shows Reverset trial results reported

HIV/AIDS Research - Single-chain antibody against HIV-1 external glycoprotein gp120 developed

HIV/AIDS Research - Soluble HIV trimeric Env fragment adopting prefusion gp41 structure developed

HIV/AIDS Risk Behavior - Adults with severe mental illness engage in risky sexual behaviors

HIV/AIDS Risk Behavior - Sexual risk behavior is high among youths in psychiatric care

HIV/AIDS Susceptibility - Screening test may be developed to determine susceptibility to HIV/AIDS

HIV/AIDS Therapy - Company begins phase III trials with aplaviroc (873140) for HIV treatment

HIV/AIDS Therapy - Company provides update of HIV/AIDS drug candidate

HIV/AIDS Therapy - Findings describe new data in HIV/AIDS therapy research

HIV/AIDS Therapy - HIV therapy success rates similar in developing and developed world

HIV/AIDS Therapy - Highly active antiretrovirals for HIV can substantially reduce AIDS rates

HIV/AIDS Therapy - Long-term safety data of antiretroviral in HIV patients with hepatitis reported

HIV/AIDS Therapy - Pharmacokinetics study results presented on once-daily HIV combination therapy

HIV/AIDS Therapy - Phorbol derivative shows promise as anti-HIV agent

HIV/AIDS Therapy - Study shows effectiveness of protease inhibitor in AIDS treatment

HIV/AIDS Therapy - Trial data on HIV antiviral therapy presented at international AIDS meeting

HIV/AIDS Treatment - Data on PA-457 drug activity after oral dose in HIV-infected patients presented

HIV/AIDS Treatment - Invirase boosted with ritonavir not associated with development of resistance

HIV/AIDS Treatment - Patients more satisfied with once-daily dosing of EPZICOM

HIV/AIDS Treatment Failure - Prevalence of virologic response disappears after 96 weeks on HAART

HIV/AIDS Vaccine - HIV-1 glycoprotein inhibits B cell chemotaxis to chemokine ligands

HIV/AIDS Vaccine - SHIV-specific T cell responses in vaccinated macaques analyzed

HIV/AIDS Vaccines - New findings in HIV/AIDS vaccines described

HIV/AIDS-Related Drug Use - Methadone treatment decreases heroin overdose-related mortality in HIV patients

HIV/AIDS-Related Kaposi Sarcoma - HAART plus liposomal doxorubicin induces tumor remission in HIV-related KS

Hepatitis B Therapy - HIV therapy tenofovir battles hepatitis B infection

Hepatitis B Therapy - Oral tenofovir stops woodchuck hepatitis virus infection in woodchucks

Hepatitis C Treatment - Development of nucleoside analog for treating hepatitis C initiated in Japan

Liver Cancer - Researchers discover link between viral infection and liver cancer

Measles Vaccines - Researchers describe findings in measles vaccines studies

Multidrug Resistant - Carbapenem use {{>=}}7 days risks multidrug resistant to P. aeruginosa

Oncology - Recent findings illuminate research in oncology

Personnel - Dr. James Koziarz joins advisory board of diagnostics company

Philanthropy - Circus to fund research on endotheliotropic herpes viruses

Tuberculous Meningitis - Isoniazid + rifampicin resistance strongly predictive of death in TB meningitis

Vaccines Adjuvant - Recent findings in vaccines adjuvant described

Virology - GB virus C protects patients coinfected with HIV

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