HIV/AIDS Research

Tests demonstrated betulinol derivative inhibits HIV-1 replication

Published in AIDS Weekly, August 29th, 2005

Preliminary experimental data from cellular tests conducted by university scientists working under a research grant sponsored by Marc Pharmaceuticals, Inc., (MPMA, MPMAW, MPMAZ) has demonstrated that a betulinol derivative inhibits HIV-1 replication by more than 90% with no evidence of detrimental changes to cell viability.

These encouraging early stage results pave the way for further preclinical studies in drug resistant strains of HIV.

Betulinol is a naturally occurring compound that is isolated from the outer layer of the bark of the white birch tree. Betulinol derivatives are formed by replacing a specific atom or group of atoms within a...

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Source: AIDS Weekly (2005-08-29)

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