AIDS Weekly
Susan Hasty, Publisher
Table of Contents . . . September 19th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in AIDS Weekly | Other Publications
HIV/AIDS Drug Development - Interferon-induced exonuclease ISG20 has antiviral activity against HIV-1
HIV/AIDS Drug Development - Pertussis toxin b-oligomer inhibits HIV infection and replication
HIV/AIDS Exposure - Genotype associated with HIV-1-exposed but uninfected serostatus identified
HIV/AIDS Viremia - HIV RNA blips during HAART may reflect ongoing viremia which impair CD4 recovery
HIV/AIDS-Related Lypodystrophy - Recombinant growth hormone reduces visceral fat in HIV-related lipodystrophy
Aging - Further research needed on HIV in an aging population
Bioterrorism - Dutch biotech, U.S. Navy to test AdVac-based vaccine against anthrax, plague
Burkitt Lymphoma - Two distinct cells of origin for EBV+/EBV- Burkitt lymphomas
Business Update - Biotech company completes corporate name change to Panacos Pharmaceuticals, Inc.
Constipation - Positive results from methylnaltrexone phase 3 clinical trial reported
Diagnostics - Hybrid capture for HPV-related cervical infection in HIV/AIDS sensitive/specific
HIV/AIDS Vaccines - Research add new data to HIV/AIDS vaccines body of knowledge
Diagnostics - TaqMan real-time PCR may be used to measure HIV RNA in resource-limited settings
Diet & Nutrition - SIV-related mortality increased in macaques consuming supplemental nutrients
Disease Control - Lipophilic antifolate trimetrexate inhibits Trypanosoma cruzi
Drug Development - Clinical research company announces completion of microdosing study
Drug Interactions - Efavirenz lowers amprenavir AUCs but NEV/IDV/RTV compensates for EFV induction
Fatty Liver Disease - Hepatic steatosis is less common where HIV and hepatitis C coinfection exist
HIV/AIDS Vaccines - Researchers' work adds to HIV/AIDS vaccines body of knowledge
Feline Immunodeficiency Virus - FIV may alter immune homeostasis by inducing chronic TNF-alpha+CD8+ activation
Feline Immunodeficiency Virus - IgG from acutely infected cats blocks mucosal FIV infection
Finance - Biopharma company reports revenue of $71.3 million
HIV Genotypes - HIV genotyping useful for classifying patients for tracking
HIV Protein - HIV-1 inhibitory protein studied, crystal structures revealed
HIV/AIDS Vaccines - Studies add new findings to HIV/AIDS vaccines body of knowledge
HIV/AIDS Diagnostics - VIDAS HIV DUO Ultra improved specificity for early HIV seroconversion detection
HIV/AIDS Drug Resistance - Multiple drug class-wide resistance with poorer survival after HAART failure
HIV/AIDS Drug Side Effect - HAART may increase risk of developing hypertension-related conditions
HIV/AIDS Epidemiology - Diversity and divergence of HIV in chronically infected women examined
HIV/AIDS Epidemiology - HIV C77G polymorphism in exon 4 of CD45 gene is prevalent in Spanish population
HIV/AIDS Vaccines - Studies advance knowledge in HIV/AIDS vaccines research
HIV/AIDS Epidemiology - HSV-2 is a primary cofactor in facilitating the spread of HIV infection
HIV/AIDS Genomics & Genetics - Prevalence of resistant mutations in Greek HIV-1 patients reported
HIV/AIDS HAART - Lopinavir CSF concentrations exceed the 50% inhibitory concentration for HIV
HIV/AIDS Hemophilia - HLA antigens predict disease progression in HIV-infected hemophilia patients
HIV/AIDS Pathogenesis - 15-Lipoxygenase-1 induction impairs HIV-1 CD4 and CXCR4 receptor expression
HIV/AIDS Pathogenesis - Amino acids identified that promote HIV TAR RNA-Tat protein complex formation
HIV/AIDS Pathogenesis - CD4 binding partially locks gp120 bridging sheet, leaves BETA2/3 strand flexible
HIV/AIDS Pathogenesis - HIV-1 FBI-1 increases NF-kappaB movement into nucleus, increases its stability
HIV/AIDS Pathogenesis - Peripheral S-phase T cells in HIV/AIDS have a central memory phenotype
HIV/AIDS Pharmacogenetics - Mutations related to altered drug pharmacokinetics influences HAART efficacy
HIV/AIDS Prevention - Intention to use condoms increased in theory-based HIV risk reduction program
HIV/AIDS Research - Milestone payment received for Reverset study 203
HIV/AIDS Research - Phase 2a clinical study of PA-457 complete, preliminary analysis reported
HIV/AIDS Vaccine - HIV type 1 Tat protein induces neutralizing antibodies
HIV/AIDS Vaccine Development - CD8+ depletion reduced virus levels of virus in SIV-vaccinated macaques
HIV/AIDS Vaccine Development - DNA prime and adenovirus boost enhance immunity to HIV immunogens
HIV/AIDS Vaccine Development - DNA vaccines expressing SIV antigens decrease viremia upon challenge
HIV/AIDS Vaccine Development - Determinants of HIV resistance to membrane-anchored peptides reported
HIV/AIDS Vaccine Development - Factors affecting retention in HIV vaccine clinical trials examined
HIV/AIDS Vaccine Development - Glycosylation affects efficacy of an Env-based vaccine against SIV
HIV/AIDS Vaccine Development - HIV vaccine reduces CD8+ expansion but improves virus control
HIV/AIDS Vaccine Development - Priming-boosting regimen enhance plasmid DNA microparticle HIV vaccines
HIV/AIDS Vaccine Development - Properties of peptide mimotopes of HIV carbohydrate antigens outlined
HIV/AIDS Vaccine Development - Replicating adenovirus-HIV vaccines elicit high cellular immunity
HIV/AIDS Vaccine Development - Treated virions elicit high-titer neutralizing antibodies
HIV/AIDS Vaccines - Recent studies add new data to HIV/AIDS vaccines research
HIV/AIDS-Associated Dementia - HIV-1 gp120 induces COX-2 expression in neuroblastoma cells via NF-KappaB/AP1
HIV/AIDS-Associated Dementia - PAR-2 induction by neuroinflammation prevents neuronal death in HIV/AIDS
HIV/AIDS-Associated Infection - Cotrimoxazole prophylaxis reduces morbidity/mortality among HIV- family members
HIV/AIDS-Associated Lipoatrophy - Lipoatrophic men 44 months post diagnosis less lipoatrophic, more hypertensive
HIV/AIDS-Associated Thrombosis - Limb salvage rate low following thrombectomy in HIV-related thrombosis
HIV/AIDS-Related Drug Adherence - Decreased drug adherence after alcohol use greater in HIV-infected persons
HIV/AIDS-Related Drug Use - Cocaine modulates DC-SIGN expression by dendritic cells in HIV-1 patients
HIV/AIDS-Related Pulmonary Hypertension - Secreted HIV gp120 may contribute to development of pulmonary hypertension
Hepatitis B Therapy - Tenofovir fights woodchuck hepatitis virus replication
Influenza Vaccines - New research in the area of influenza vaccines detailed
Kaposi Sarcoma-Associated Herpesvirus - Researchers provide details of new studies and findings in the area of kaposi sarcoma-associated herpesvirus
Liver Cirrhosis - HIV coinfection cuts survival in those with HCV-related decompensated cirrhosis
Marketing - Maker of rapid test kits for HIV, hepatitis, others, signs marketing agreement
Nevirapine Resistance Mutation - NVP resistance after single dose higher in women with HIV-1 subtype C than A/D
Sexual & Reproductive Health - Predictors of STD vaccine acceptability investigated
TB Epidemiology - WHO declares TB an emergency in Africa
Vaccine Vectors - Vectors from rare adenovirus serotypes may be useful for vaccines
Virology - Recent findings in virology described
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