Published in AIDS Weekly, September 26th, 2005
"Breakdown of the blood-brain barrier (BBB) is commonly seen in patients with HIV-associated dementia (HAD) despite the lack of productive infection of the brain endothelium. It is likely that secreted viral products play a major role in BBB damage and the development of HAD.
"Our results showed that treatment of cultured human brain endothelial cells...
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