Brain Cancer
Drug efflux transporters play role in drug resistance in brain diseases
Published in AIDS Weekly, September 26th, 2005
According to a study from Germany, "Resistance to drug treatment is an important hurdle in the therapy of many brain disorders, including brain cancer, epilepsy, schizophrenia, depression and infection of the brain with HIV. Consequently, there is a pressing need to develop new and more effective treatment strategies."
"Mechanisms of resistance that operate in cancer and infectious diseases might also be relevant in drug-resistant brain disorders. In particular, drug efflux transporters that are expressed at the blood-brain barrier limit the ability of many drugs to access the...
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Source: AIDS Weekly (2005-09-26)
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