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AIDS Weekly

Susan Hasty, Publisher

Table of Contents . . . October 3rd, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in AIDS Weekly | Other Publications

HIV/AIDS Pathogenesis - HIV-1 Vpr impairs dendritic cell maturation and T cell activation

HIV/AIDS Pathogenesis - Limited HIV evolution in persistently targeted CD8 epitopes in chronic infection

HIV/AIDS Prognosis - Generated CD8+ cells from HIV-1+ neonates not associated with improved outcome

Addiction Medicine - Drug users in Ireland remain vulnerable to bloodborne pathogens

Antiviral Resistance - Prevalence of resistance-associated mutations in HIV patients reported

Breast Feeding - Breast milk provides ARV exposure to infants, but impact not yet understood

Clinical Trials - Encouraging immune response seen in "Prime/Boost" phase I HIV vaccine study

Clinical Trials - Favorable clinical results reported for HIV vaccine

Clinical Trials - Potential nucleoside analogue drug for hepatitis B, HIV enters Phase 2 studies

HIV/AIDS Pathogenesis - Researchers provide details of new studies and findings in the area of HIV/AIDS pathogenesis

Diagnostics - Immunoblot test detects antiToxoplasma gondii IgG in saliva

Drug Development - Results of phase I AIDS vaccine study released

Drug Development - U.S. FDA allows IND for phase III trial of antifungal agent

Epidemiology - Origin of SIVmac and SIVstm unraveled

Feline Immunodeficiency Virus Pathogenesis - FIV causes neuroinflammation and neuronal injury in dorsal root ganglia

Finance - Venture fund company makes seed investment in Azidex Pharmaceuticals

HIV/AIDS Pathogenesis - Researchers report details of new studies and findings in the area of HIV/AIDS pathogenesis

Gastroenterology - Liposomal doxorubicin more effective in GI KS than in cutaneous AIDS-related KS

Genetics & Genomics - Genome-wide RRV transcription profile parallels the profile for KSHV

HIV/AIDS Coinfection - IL-6 and HIV RNA predict anorexia/wasting in adults with pulmonary tuberculosis

HIV/AIDS Diagnosis - Prevalence of HIV/AIDS among black women explored

HIV/AIDS Diagnosis - Study reveals racial disparities in prenatal HIV testing

HIV/AIDS Infection - HIV-1 reinfections occur almost as commonly as first infections

HIV/AIDS Infection - Outbreak of West African HIV recombinant in Uzbekistan reported

HIV/AIDS Pathogenesis - Broad cross-clade T-cell responses to gag in HIV-1 non-B clades

HIV/AIDS Pathogenesis - Findings in HIV/AIDS pathogenesis provide new insights

HIV/AIDS Pathogenesis - HIV Nef induces rapid internalization of T-cell coreceptor CD8alphabeta

HIV/AIDS Pathogenesis - HIV-1 Nef induces genes involved in cholesterol biosynthesis in infected T cells

HIV/AIDS Pathogenesis - HIV-1 Tat downregulates apical caspase-10/upregulates C-flip in T Cells

HIV/AIDS Pathogenesis - HIV-1 vpr induces degradation of UNG and SMUG uracil-DNA glycosylases

HIV/AIDS Pathogenesis - Inhibition of HIV-1 3'ss A2 splicing necessary for viral replication

HIV/AIDS Pathogenesis - Myeloid/plasmacytoid DCs transfer HIV-1 preferentially to Ag-specific CD4+ cells

HIV/AIDS Pathogenesis - Nef from diverse lentiviruses downmodulates CXCR4 to inhibit migration to SDF-1

HIV/AIDS Pathogenesis - PARP-1 required for HIV-1 integration near the centromere region

HIV/AIDS Pathogenesis - Palmitoylation of HIV-1 Env cytoplasmic tail not essential for virus life cycle

HIV/AIDS Pathogenesis - Primary CD4+ cell activation increases LFA-1 affinity/avidity states in HIV/AIDS

HIV/AIDS Pathogenesis - SIV and HIV-2 Nef alleles enhance viral infectivity and replication

HIV/AIDS Pathogenesis - Significant proportion of very early nonsynonymous HIV mutations selected by CTL

HIV/AIDS Pathogenesis - Ubiquitylation of Cdk9 By Skp2 facilitates optimal HIV-1 Tat transactivation

HIV/AIDS Pathogenesis - Vpr-mediated cell cycle arrest important for HIV replication and pathogenesis

HIV/AIDS Prevention - Elevated chemokines and T cells may provide resistance against HIV

HIV/AIDS Prevention - New therapies evaluated for preventing mother-to-child transmission of HIV

HIV/AIDS Prevention - Postexposure prophylaxis compliance low for sexual assault in South Africa

HIV/AIDS Research - Concerted integration analyzed, channeling role of viral DNA processing defined

HIV/AIDS Therapy - Association made between alcohol consumption and medication adherence

HIV/AIDS Therapy - Medication adherence assessed with psychosocial variables in HIV patients

HIV/AIDS Therapy - New device offers friendly medication reminder to HIV patients

HIV/AIDS Therapy - Study examined changes in childbearing of HIV-infected mothers over time

HIV/AIDS Transmission - Link between mother to child transmission of HIV via amniotic fluid explored

HIV/AIDS Transmission - Reports add new data to HIV/AIDS transmission research

HIV/AIDS Vaccine Development - Antigen-presenting cells do not modulate immune responses

HIV/AIDS Vaccine Development - Glycosylation affected the efficacy of vaccine against SIV

HIV/AIDS Vaccine Development - HIV canarypox vaccine is safe and immunogenic in HIV-infected patients

HIV/AIDS Vaccine Development - Immunogenicity of HIV-1 envelope glycoprotein complex evaluated

HIV/AIDS Vaccine Development - Mucosal alloimmunization inhibits SIV infectivity

HIV/AIDS Vaccine Development - Properties of peptide mimotopes of HIV carbohydrate antigens reported

HIV/AIDS Vaccine Development - Replicating adenovirus-HIV vaccines are better at eliciting immunity

HIV/AIDS Vaccine Development - Vaccine effect on HIV-1 viremia after antiretroviral therapy reported

HIV/AIDS Vaccine Development - Virions with HIV Env induce high-titer neutralizing antibody responses

HIV/AIDS Vaccines - Researchers' findings advance HIV/AIDS vaccines research

HIV/AIDS-Associated Cryptococcosis - Cryptococcosis incidence decreased in HIV+ persons prior to HAART era

HIV/AIDS-Associated Dementia - HIV-1 Env compartmentalization increased in HIV-1-associated dementia

HIV/AIDS-Associated Mycobacteriosis - Parotid mycobacteriosis frequently caused by MTB in advanced AIDS

HIV/AIDS-Herpes Simplex Virus Type 2 Coinfection - Treating HSV-2 in HIV-coinfected persons delays need for HAART

HIV/AIDS-Related Dementia - HIV-1 gp120 and Tat induce oxidative stress in brain endothelial cells

HIV/AIDS-Related Herpes Simplex Virus Type 2 - Macaque dendritic cells can become infected by herpes simplex virus type 2

Health Prevention - Rumor of shortage of condoms in Uganda is untrue

Healthcare Costs - AIDS foundation comments on high price of protease inhibitor tipranavir compound

Hepatitis B Therapy - Recent findings in hepatitis b therapy provide new insights

Influenza Vaccine Efficacy - Influenza vaccines are safe and effficacious in HIV-positive patients

Philanthropy - Pharma company partners with pharmacies to expand Hurricane Katrina relief

Virology - Antigenic stimulation reactivates replication of archived SIV genomes

Virology - Foamy virus Bet proteins inhibit innate antiretroviral defense factors

Virology - Researchers report details of new studies and findings in the area of virology

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