HIV/AIDS Pathogenesis
SIV and HIV-2 Nef alleles enhance viral infectivity and replication
Published in AIDS Weekly, October 3rd, 2005
According to recent research published in the Journal of Virology, "The nef gene of the pathogenic simian immunodeficiency virus (SIV) mac239 clone has been well characterized. Little is known, however, about the function of nef alleles derived from naturally SIVsm-infected sooty mangabeys (Cercocebus atys) and from human immunodeficiency virus type 2 (HIV-2)-infected individuals."
"Addressing this, we demonstrate that, similarly to the SIVmac239 nef, primary SIVsm and HIV-2 nef alleles downmodulate cell surface expression of human CD4, CD28, CD3,...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of AIDS Weekly
Source: AIDS Weekly (2005-10-03)
More Articles from AIDS Weekly
- HIV/AIDS Pathogenesis
HIV-1 Vpr impairs dendritic cell maturation and T cell activation - HIV/AIDS Pathogenesis
Limited HIV evolution in persistently targeted CD8 epitopes in chronic infection - HIV/AIDS Prognosis
Generated CD8+ cells from HIV-1+ neonates not associated with improved outcome - Addiction Medicine
Drug users in Ireland remain vulnerable to bloodborne pathogens - Antiviral Resistance
Prevalence of resistance-associated mutations in HIV patients reported - Breast Feeding
Breast milk provides ARV exposure to infants, but impact not yet understood - More from this issue of AIDS Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
