Autoimmune Disease

Key protein opens door to new treatments

Published in AIDS Weekly, October 10th, 2005

It is known that a key protein in the immune system, C3, bonds with and interacts with up to 40 other proteins and receptors in the blood. But until now it has not been understood what the significance of these bonds might be.

In the latest issue of the scientific journal Nature, a Swedish-Dutch research team has laid bare the crystal structure of the protein, which may lead to tailor-made treatments for autoimmune diseases.

Scientists at Uppsala University, in collaboration with the universities of Utrecht and Leiden in the Netherlands and Kalmar in Sweden have managed to describe the crystal structure of one of the key proteins in the...

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Source: AIDS Weekly (2005-10-10)

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