HIV/AIDS Epidemiology
HIV-1 group M isolates are 100-fold-more fit than group 0 or HIV-2 strains
Published in AIDS Weekly, October 17th, 2005
According to recent research from the United States, "The main (M) group of human immunodeficiency virus type 1 (HIV-1) is responsible for the global AIDS epidemic while HIV-1 group O (outlier) and HIV type 2 are endemic only in west and central Africa.
"The failure of HIV-2 and especially HIV-1 group O to spread following the initial zoonotic jumps is not well understood. This study was designed to examine the relative replicative capacities between these human lentiviruses."
"A pairwise competition experiment was performed with peripheral blood...
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Source: AIDS Weekly (2005-10-17)
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