HIV/AIDS Pathogenesis
NKp44L expression correlates with CD4 depletion and HIV RNA increase
Published in AIDS Weekly, October 24th, 2005
"HIV infection leads to a state of chronic immune activation and progressive deterioration in immune function, manifested most recognizably by the progressive depletion of CD4+ T cells.
"A substantial percentage of natural killer (NK) cells from patients with HIV infection are activated and express the natural cytotoxicity receptor (NCR) NKp44," scientists in France report.
"Here we show that a cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is...
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Source: AIDS Weekly (2005-10-24)
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