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HIV/AIDS Vaccine Development

Efficacy of recombinant glycoprotein 120 vaccine reported

Published in AIDS Weekly, October 24th, 2005

Researchers report results of a clinical trial assessing the efficacy of a recombinant glycoprotein 120 vaccine in a recent issue of the Journal of Infectious Diseases.

"The first trial of the efficacy of a human immunodeficiency virus (HIV)-1 vaccine was conducted in North America and the Netherlands between 1998 and 2003. This multicenter, randomized, placebo-controlled trial of a recombinant glycoprotein 120 vaccine included 5,403 initially HIV-negative volunteers who were monitored for 3 years," investigators in the United States and Canada report.

"The 368 subjects who acquired HIV-1 infection were monitored for 2 years by use of the...

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