HIV/AIDS Transmission
Cervicovaginal culture system determines HIV transmission events after exposure
Published in AIDS Weekly, October 24th, 2005
"We have developed human cervicovaginal organ culture systems to examine the initiating events in HIV transmission after exposure to various sources of HIV infectivity, including semen. Newly infected cells were detected in the cervical submucosa 3-4 days after exposure to a primary HIV isolate.
"At earlier times, extensive and stable binding occurred when cervical surfaces were exposed to virions or seminal cells. Cervical mucus provided some protection for the endocervical surface, by physically trapping virions and seminal cells," scientists in...
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Source: AIDS Weekly (2005-10-24)
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