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HIV/AIDS Transmission

Immunophenotyping helps predicts risk of perinatal HIV transmission

Published in AIDS Weekly, October 24th, 2005

Immunophenotyping predicts the risk of perinatal HIV transmission.

"This study of a subset of women and infants participating in National Institutes of Health Pediatric AIDS Clinical Trials Group protocol 185 evaluated lymphocyte phenotypic markers of immune activation and differentiation to determine their association with the likelihood of human immunodeficiency virus (HIV) transmission from the women to their infants and the potential for early identification and/or prognosis of infection in the infants.

"Lymphocytes from 215 human immunodeficiency virus type 1 (HIV)-infected women and 192 of their infants were analyzed by flow cytometry with an...

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