Adverse Drug Reaction
Drugs raise mitochondrial toxicity risk in HIV/hepatitis C-coinfected patients
Published in AIDS Weekly, October 24th, 2005
Researchers in France conducted a study "to evaluate the incidence, clinical features, and risk factors for symptomatic mitochondrial toxicity in HIV/(HCV)-coinfected patients receiving anti-HCV therapy. All cases of symptomatic mitochondrial toxicity reported in 416 patients participating in an open, randomized trial of peg-interferon alpha-2b plus ribavirin vs. interferon alpha-2b plus ribavirin for 48 weeks were reviewed."
"Associations with antiretroviral treatments and with clinical and laboratory findings were sought by univariate and multivariate...
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Source: AIDS Weekly (2005-10-24)
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