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HIV/AIDS-Associated Infection

TSP/HAM should be considered in HIV patients with myelopathy and normal CD4 counts

Published in AIDS Weekly, October 31st, 2005

Tropical spastic paraparesis/human T leukemia virus type 1-associated myelopathy should be considered in HIV/AIDS patients with myelopathy and normal CD4 counts.

"Tropical spastic paraparesis/human T leukemia virus type 1 (HTLV-1)-associated myelopathy (TSP/HAM) is rarely reported in the United States. The causative agents of TSP/HAM are HTLV-1 and, possibly, its cosmopolitan variant, human T leukemia virus type 2 (HTLV-2)," scientists writing in the journal Clinical Infectious Diseases report.

"Among HTLV-1-or HTLV-2-monoinfected individuals, the estimated lifetime risk for development of TSP/HAM is <2%. However, it has been suggested that...

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