Susan Hasty, Publisher
Table of Contents . . . November 14th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in AIDS Weekly | Other Publications
Genetics & Genomics - Genotype combination advantageous in resisting HIV-1 transmission
HIV/AIDS Pathogenesis - HIV-1 variants from single plasma samples have various neutralization sensitivities
HIV/AIDS Prevention - Vaginal microbicide phase III trial underway, 10,000 women to be enrolled
HIV/AIDS Topical Microbicide - Topically applied amphibian-derived antimicrobial peptides inhibit HIV infection
HIV/AIDS-Related Lipodystrophy - Metformin improves lipid profiles in HIV-related lipodystrophy
Awards - Tulane receives millions for international health and tropical medicine research
Bacterial Vaginosis - Amsel criteria poor predictor compared to other diagnositic tests for bacterial vaginosis
Bacteriology - M. intracellulare infects women increasingly beyond menopause
Behavioral Medicine - Transtheoretical model promotes integrated pregnancy and STD prevention in family planning setting
Blood Safety - Blood screening and vaccines lower the risk of transfusion-transmitted infections in Italy
Business & Finance - Biotech company announces final settlement of 4-year Serostim investigation
HIV/AIDS Pathogenesis - New findings in HIV/AIDS pathogenesis described
Business & Finance - Genetics therapy-focused biotech company completes $30 million financing
Clinical Trials - DNA 'prime-boost' vaccine technology enters phase 2 clinical trial for HIV
Clinical Trials - Phase 2 testing of HIV vaccine developed with Vaccine Research Center initiated
Collaborations - Alliance formed to combat infectious diseases
Dental Research - Study shows HIV-positive and at-risk women tend to avoid dental care
Disease Control - Public opinion supports condom education in Indiana public schools
HIV/AIDS Pathogenesis - Researchers report details of new studies and findings in the area of HIV/AIDS pathogenesis
Drug Development - Intratect approved for nine European countries
Epidemiology - Indigenous Western Australians have greater HIV transmission risk than nonindigenous people
Finance - Virus-focused biopharma company reports Q3 2004 Fuzeon net sales of $48.9 million
Genetics & Genomics - A protein in St. John's wort is found to suppress HIV-1 gene expression
HIV/AIDS Antiretroviral - UC-781 inhibits HIV-1 infection of cervical tissue and dissemination by migratory cells
HIV/AIDS Diagnosis - Reports advance knowledge in HIV/AIDS diagnosis research
HIV/AIDS Diagnostics - Genotypic assay determines all HIV-1 protease and reverse transcriptase subtypes
HIV/AIDS Diagnostics - Rapid test kit increases presence in South Africa; moves into East Africa
HIV/AIDS Diagnostics - Ultrasensitive p24 antigen ELISA diagnoses subtype C HIV-1 infection in infants
HIV/AIDS Drug Development - Covalent stabilization of coiled coils of the HIV gp41 N region inhibits viral infection
HIV/AIDS Drug Development - Pleiotrophin inhibits HIV infection by binding the cell surface-expressed nucleolin
HIV/AIDS Drug Development - Two HIV-1 entry inhibitors prevent gp120 binding to CD4
HIV/AIDS Drug Mutations - HIV RT L74V mutation reduces ATP-dependent removal of ZDV-MP from newly synthesized viral DNA
HIV/AIDS Drug Mutations - Mutations that abrogate HIV-1 RT dimerization affect maturation of the RT heterodimer
HIV/AIDS Drug Resistance - Molecular footprint of drug-selective pressure identified in HIV transmission chain
HIV/AIDS Drug Resistance - Reverse transcriptase inhibitors act together to increase HIV-1 mutation frequencies
HIV/AIDS Epidemiology - HIV prevalence associated with increased intravenous drug use increasing in Mexico
HIV/AIDS Epidemiology - Monte Carlo model estimates the natural variation in HIV infection
HIV/AIDS Exposure - CD91 expression increased on monocytes of exposed yet HIV-1-seronegative persons
HIV/AIDS Neurology - HIV-1 species barrier does not extend to uptake by the blood-brain barrier
HIV/AIDS Pathogenesis - Cul5-E3 ligase is a common pathway hijacked by HIV-1 Vif to defeat h-A3F and h-A3G
HIV/AIDS Pathogenesis - Findings in HIV/AIDS pathogenesis provide new insights
HIV/AIDS Pathogenesis - HIV infection route is a factor in the broad humoral immune response in intravenous drug users
HIV/AIDS Pathogenesis - HIV reactivation by phorbol esters or T-cell receptor ligation requires PKCalpha and PKCtheta
HIV/AIDS Pathogenesis - HIV-1 Nef-induced FasL induction and bystander killing requires p38 MAPK activation
HIV/AIDS Pathogenesis - HLA-A2 downmodulation mechanisms similar in primary T cells and macrophages
HIV/AIDS Pathogenesis - Lipid raft integrity critical for HIV Env and Gag coclustering and virological synapse assembly
HIV/AIDS Pathogenesis - Morphine inhibits anti-HIV activity of CD8+ cells in HIV latently infected cells
HIV/AIDS Pathogenesis - Type I IFN production is profoundly and transiently impaired in primary HIV-1 infection
HIV/AIDS Pathogenesis - Very early in life, HIV-1-specific CTL can select for viral escape variants
HIV/AIDS Pediatrics Research - Decreased bone mass in HIV-infected children due to disease severity and growth delay
HIV/AIDS Prevention - India's HIV/AIDS pandemic threatens economic and social fabric
HIV/AIDS Prognosis - APOBEC3G/CEM15 mRNA levels inversely associated with HIV viremia
HIV/AIDS Prognosis - HLA-B63 is associated with low HIV RNA
HIV/AIDS Research - Procyon announces positive preclinical results for lead HIV protease inhibitor
HIV/AIDS Therapy - AIDS Support Organization opens AIDS counseling and training center in Uganda
HIV/AIDS Therapy - Abacavir/lamivudine/zidovudine improves HAART adherence in HIV-1-infected patients
HIV/AIDS Therapy - HIV protease inhibitor ritonavir increases endothelial monolayer permeability
HIV/AIDS Therapy - Trials comparing therapies for HIV/AIDS, related Kaposi's sarcoma are urgently needed in sub-Saharan Africa
HIV/AIDS Therapy - Updated HIV guidelines support fusion inhibitor plus protease inhibitor therapy
HIV/AIDS Vaccine Development - CD8+ lymphocytes do not protect against acute SIV superinfection
HIV/AIDS Vaccine Development - HIV trials feasible with fewer animals if subjects repeatedly challenged with low doses
HIV/AIDS Vaccine Development - HIV-1 Env clones developed for standardized assessments of vaccine-elicited neutralizing antibodies
HIV/AIDS Vaccine Development - Research collaboration formed to develop topical delivery of therapeutic DNA vaccines
HIV/AIDS-Related Atherosclerosis - HIV-1 Tat induces VCAM-1 expression in pulmonary artery endothelial cells
HIV/AIDS-Related Infection - Incidence of esophageal candidiasis in AIDS patients in Europe is declining
HIV/AIDS-Related Infection - Nocardiosis to be considered in HIV patients with low CD4 counts
HIV/AIDS-Related Infection - Oral lesions are indicators of infection in HIV/AIDS
HIV/AIDS-Related Kaposi Sarcoma - AIDS-Kaposi sarcoma patients treated with HAART have a high clinical response rate
HIV/AIDS-Related Mental Health - Depression is not associated with HIV disease status
Immunodeficiency - Natural killer cell-mediated cytotoxicity spawns liver failure
Malaria Drugs - HIV-1 protease inhibitors have antimalarial activity
Philanthropy - New HIV/AIDS collaboration launched in Kenya
Sociology Research - Many health workers in Nigeria discriminate against patients with HIV/AIDS
Tuberculosis - Recurrent tuberculosis in HIV-infected children is common in a high-burden TB setting
Virology - HIV and hepatitis C virus infection elicit similarities in natural killer cells
Virology - Liver enzyme flares require scrutiny in HIV-HCV coinfected patients beginning therapy
Virology - Rab9 GTPase required for HIV-1, filovirus and measles virus replication
Virology - Researchers publish new studies and findings in the area of virology
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